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1

Protein–protein interactions in polyketide synthase–nonribosomal peptide synthetase hybrid assembly lines

Miyanaga, Akimasa, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Natural Product Reports

Year:

2018

Language:

english

File:

PDF, 5.35 MB

english, 2018

2

Genome Mining Reveals Two Novel Bacterial Sesquiterpene Cyclases: (−)-Germacradien-4-ol and (−)-epi-α-Bisabolol Synthases from Streptomyces citricolor

Dr. Chiaki Nakano, Prof. Fumitaka Kudo, Prof. Tadashi Eguchi, Prof. Yasuo Ohnishi

Journal:

Year:

2011

Language:

english

File:

PDF, 234 KB

english, 2011

3

The Last Step of Kanamycin Biosynthesis: Unique Deamination Reaction Catalyzed by the α-Ketoglutarate-Dependent Nonheme Iron Dioxygenase KanJ and the NADPH-Dependent Reductase KanK

Hilda Sucipto, Prof. Dr. Fumitaka Kudo, Prof. Dr. Tadashi Eguchi

Journal:

Angewandte Chemie

Year:

2012

Language:

english

File:

PDF, 512 KB

english, 2012

4

Five-membered Cyclitol Phosphate Formation by a myo-Inositol Phosphate Synthase Ortholog in the Biosynthesis of the Carbocyclic Nucleoside Antibiotic Aristeromycin

Kudo, Fumitaka, Tsunoda, Takeshi, Takashima, Makoto, Eguchi, Tadashi

Journal:

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

5

First Total Synthesis of Actinorhodin

Ninomiya, Mamiko, Ando, Yoshio, Kudo, Fumitaka, Ohmori, Ken, Suzuki, Keisuke

Journal:

Angewandte Chemie International Edition

Year:

2019

Language:

english

File:

PDF, 2.77 MB

english, 2019

6

Involvement of Two Distinct N-Acetylglucosaminyltransferases and a Dual-Function Deacetylase in Neomycin Biosynthesis

Kenichi Yokoyama, Yasuhito Yamamoto, Fumitaka Kudo, Tadashi Eguchi

Journal:

Year:

2008

Language:

english

File:

PDF, 254 KB

english, 2008

7

Cloning and Characterization of the Biosynthetic Gene Cluster of 16-Membered Macrolide Antibiotic FD-891: Involvement of a Dual Functional Cytochrome P450 Monooxygenase Catalyzing Epoxidation and Hydroxylation

Fumitaka Kudo, Atsushi Motegi, Kazutoshi Mizoue, Tadashi Eguchi

Journal:

Year:

2010

Language:

english

File:

PDF, 426 KB

english, 2010

8

Corrigendum: Cloning and Characterization of the Biosynthetic Gene Cluster of 16-Membered Macrolide Antibiotic FD-891: Involvement of a Dual Functional Cytochrome P450 Monooxygenase Catalyzing Epoxidation and Hydroxylation

Fumitaka Kudo, Atsushi Motegi, Kazutoshi Mizoue, Tadashi Eguchi

Journal:

Year:

2010

Language:

english

File:

PDF, 80 KB

english, 2010

9

ChemInform Abstract: Biosynthetic Genes for Aminoglycoside Antibiotics

Fumitaka Kudo, Tadashi Eguchi

Journal:

Year:

2010

File:

PDF, 15 KB

2010

10

Role of glutamate 243 in the active site of 2-deoxy-scyllo-inosose synthase from Bacillus circulans

Toshifumi Hirayama, Fumitaka Kudo, Zhen Huang, Tadashi Eguchi

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 638 KB

english, 2007

11

Magnetic properties and distribution of thermal averages of spins in the one-dimensional random mixture of Ising spins of S = 1 and 12

Tomoshige Kudo, Fumitaka Matsubara, Shigetoshi Katsura

Journal:

Physica A: Statistical Mechanics and its Applications

Year:

1978

Language:

english

File:

PDF, 650 KB

english, 1978

12

Unique O-ribosylation in the biosynthesis of butirosin

Fumitaka Kudo, Takuya Fujii, Shunsuke Kinoshita, Tadashi Eguchi

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 698 KB

english, 2007

13

Biosynthetic pathway of 24-membered macrolactam glycoside incednine

Makoto Takaishi, Fumitaka Kudo, Tadashi Eguchi

Journal:

Year:

2008

Language:

english

File:

PDF, 426 KB

english, 2008

14

Macrolactam formation catalyzed by the thioesterase domain of vicenistatin polyketide synthase

Fumitaka Kudo, Takashi Kitayama, Katsumi Kakinuma, Tadashi Eguchi

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

15

An expeditious chemo-enzymatic route from glucose to catechol by the use of 2-deoxy-scyllo-inosose synthase

Katsumi Kakinuma, Eriko Nango, Fumitaka Kudo, Yoshitaka Matsushima, Tadashi Eguchi

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 105 KB

english, 2000

16

Precursor-Directed Biosynthesis: Biochemical Basis of the Remarkable Selectivity of the Erythromycin Polyketide Synthase toward Unsaturated Triketides

David E Cane, Fumitaka Kudo, Kenji Kinoshita, Chaitan Khosla

Journal:

Chemistry & Biology

Year:

2002

Language:

english

File:

PDF, 393 KB

english, 2002

17

Comparative study of nonbridging and bridging external fixators for unstable distal radius fractures

Chozo Uchikura, Jun Hirano, Fumitaka Kudo, Kazuhiko Satomi, Takaya Ohno

Journal:

Journal of Orthopaedic Science

Year:

2004

Language:

english

File:

PDF, 244 KB

english, 2004

18

Reconstruction using bone lengthening of the residual digit after amputation for the treatment of digital malignant tumors

Chozo Uchikura, Jun Hirano, Fumitaka Kudo, Kazuo Mochizuki, Keiji Suzuki, Kazuhiko Satomi

Journal:

Journal of Orthopaedic Science

Year:

2006

Language:

english

File:

PDF, 275 KB

english, 2006

19

In vivo imaging of microglial activation using a peripheral benzodiazepine receptor ligand: [11C]PK-11195 and animal PET following ethanol injury in rat striatum

Hiroshi Toyama, Kentaro Hatano, Hiromi Suzuki, Masanori Ichise, Sotaro Momosaki, Gen Kudo, Fumitaka Ito, Takashi Kato, Hiroshi Yamaguchi, Kazuhiro Katada, Makoto Sawada, Kengo Ito

Journal:

Annals of Nuclear Medicine

Year:

2008

Language:

english

File:

PDF, 343 KB

english, 2008

20

Two activated stages of microglia and PET imaging of peripheral benzodiazepine receptors with [11C]PK11195 in rats

Fumitaka Ito, Hiroshi Toyama, Gen Kudo, Hiromi Suzuki, Kentaro Hatano, Masanori Ichise, Kazuhiro Katada, Kengo Ito, Makoto Sawada

Journal:

Annals of Nuclear Medicine

Year:

2010

Language:

english

File:

PDF, 320 KB

english, 2010

21

Biosynthesis of 2-Deoxystreptamine by Three Crucial Enzymes in Streptomyces fradiae NBRC 12773

Kudo, Fumitaka, Yamamoto, Yasuhito, Yokoyama, Kenichi, Eguchi, Tadashi, Kakinuma, Katsumi

Journal:

The Journal of Antibiotics

Year:

2005

Language:

english

File:

PDF, 803 KB

english, 2005

22

Extended Sequence and Functional Analysis of the Butirosin Biosynthetic Gene Cluster in Bacillus circulans SANK 72073

Kudo, Fumitaka, Numakura, Mario, Tamegai, Hideyuki, Yamamoto, Hideki, Eguchi, Tadashi, Kakinuma, Katsumi

Journal:

The Journal of Antibiotics

Year:

2005

Language:

english

File:

PDF, 152 KB

english, 2005

23

Biosynthesis of 2-Deoxystreptamine-containing Antibiotics in Streptoalloteichus hindustanus JCM 3268: Characterization of 2-Deoxy-scyllo-inosose Synthase

Hirayama, Toshifumi, Tamegai, Hideyuki, Kudo, Fumitaka, Kojima, Kazumasa, Kakinuma, Katsumi, Eguchi, Tadashi

Journal:

The Journal of Antibiotics

Year:

2006

Language:

english

File:

PDF, 157 KB

english, 2006

24

Cloning of the Pactamycin Biosynthetic Gene Cluster and Characterization of a Crucial Glycosyltransferase Prior to a Unique Cyclopentane Ring Formation

Kudo, Fumitaka, Kasama, Yuko, Hirayama, Toshifumi, Eguchi, Tadashi

Journal:

The Journal of Antibiotics

Year:

2007

Language:

english

File:

PDF, 260 KB

english, 2007

25

Enzymatic activity of a glycosyltransferase KanM2 encoded in the kanamycin biosynthetic gene cluster

Kudo, Fumitaka, Sucipto, Hilda, Eguchi, Tadashi

Journal:

The Journal of Antibiotics

Year:

2009

Language:

english

File:

PDF, 274 KB

english, 2009

26

Enzymatic preparation of neomycin C from ribostamycin

Kudo, Fumitaka, Kawashima, Taiki, Yokoyama, Kenichi, Eguchi, Tadashi

Journal:

The Journal of Antibiotics

Year:

2009

Language:

english

File:

PDF, 183 KB

english, 2009

27

Biosynthetic genes for aminoglycoside antibiotics

Kudo, Fumitaka, Eguchi, Tadashi

Journal:

The Journal of Antibiotics

Year:

2009

Language:

english

File:

PDF, 659 KB

english, 2009

28

Cloning of the biosynthetic gene cluster for naphthoxanthene antibiotic FD-594 from Streptomyces sp. TA-0256

Kudo, Fumitaka, Yonezawa, Takanori, Komatsubara, Akiko, Mizoue, Kazutoshi, Eguchi, Tadashi

Journal:

The Journal of Antibiotics

Year:

2010

Language:

english

File:

PDF, 587 KB

english, 2010

29

The Last Step of Kanamycin Biosynthesis: Unique Deamination Reaction Catalyzed by the α-Ketoglutarate-Dependent Nonheme Iron Dioxygenase KanJ and the NADPH-Dependent Reductase KanK

Hilda Sucipto, Prof. Dr. Fumitaka Kudo, Prof. Dr. Tadashi Eguchi

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 519 KB

english, 2012

30

Biosynthetic pathway of macrolactam polyketide antibiotic cremimycin

Keita Amagai, Fumitaka Kudo, Tadashi Eguchi

Journal:

Year:

2011

Language:

english

File:

PDF, 468 KB

english, 2011

31

A Unique Pathway for the 3-Aminobutyrate Starter Unit from l -Glutamate through β-Glutamate during Biosynthesis of the 24-Membered Macrolactam Antibiotic, Incednine

Takaishi, Makoto, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Organic Letters

Year:

2012

Language:

english

File:

PDF, 293 KB

english, 2012

32

Management of hepatitis C; Report of the Consensus Meeting at the 45th Annual Meeting of the Japan Society of Hepatology (2009)

Izumi Namiki, Shuhei Nishiguchi, Keisuke Hino, Fumitaka Suzuki, Hiromitsu Kumada, Yoshihito Itoh, Yusuhiro Asahina, Akihiro Tamori, Naoki Hiramatsu, Norio Hayashi, Masatoshi Kudo

Journal:

Hepatology Research

Year:

2010

Language:

english

File:

PDF, 316 KB

english, 2010

33

Novel versipelostatin analogues from Streptomyces versipellis 4083-SVS6

Ping Zhao, Jun’ya Ueda, Motoki Takagi, Fumitaka Kudo, Kazuo Shin-ya, Tomohisa Kuzuyama

Journal:

Journal of Biotechnology

Year:

2008

Language:

english

File:

PDF, 76 KB

english, 2008

34

[Methods in Enzymology] Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates Volume 459 || Chapter 20 Biosynthetic Enzymes for the Aminoglycosides Butirosin and Neomycin

Year:

2009

Language:

english

File:

PDF, 627 KB

english, 2009

35

A New Family of Glucose-1-phosphate/Glucosamine-1-phosphate Nucleotidylyltransferase in the Biosynthetic Pathways for Antibiotics

Kudo, Fumitaka, Kawabe, Kenichi, Kuriki, Hisako, Eguchi, Tadashi, Kakinuma, Katsumi

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 309 KB

english, 2005

36

Identification of the incednine biosynthetic gene cluster: characterization of novel β-glutamate-β-decarboxylase IdnL3

Takaishi, Makoto, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

The Journal of Antibiotics

Year:

2013

Language:

english

File:

PDF, 894 KB

english, 2013

37

A Single PLP-Dependent Enzyme PctV Catalyzes the Transformation of 3-Dehydroshikimate into 3-Aminobenzoate in the Biosynthesis of Pactamycin

Hirayama, Akane, Eguchi, Tadashi, Kudo, Fumitaka

Journal:

Year:

2013

Language:

english

File:

PDF, 300 KB

english, 2013

38

A Natural Protecting Group Strategy To Carry an Amino Acid Starter Unit in the Biosynthesis of Macrolactam Polyketide Antibiotics

Shinohara, Yuji, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 2.19 MB

english, 2011

39

A Unique Amino Transfer Mechanism for Constructing the β-Amino Fatty Acid Starter Unit in the Biosynthesis of the Macrolactam Antibiotic Cremimycin

Amagai, Keita, Takaku, Ryoma, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Year:

2013

Language:

english

File:

PDF, 910 KB

english, 2013

40

The crystal structure of the amidohydrolase VinJ shows a unique hydrophobic tunnel for its interaction with polyketide substrates

Shinohara, Yuji, Miyanaga, Akimasa, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Year:

2014

Language:

english

File:

PDF, 1.19 MB

english, 2014

41

Biosynthesis of natural products containing β-amino acids

Kudo, Fumitaka, Miyanaga, Akimasa, Eguchi, Tadashi

Journal:

Natural Product Reports

Year:

2014

Language:

english

File:

PDF, 2.18 MB

english, 2014

42

Mechanistic Study on the Reaction of a Radical SAM Dehydrogenase BtrN by Electron Paramagnetic Resonance Spectroscopy †

Yokoyama, Kenichi, Ohmori, Daijiro, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Year:

2008

Language:

english

File:

PDF, 435 KB

english, 2008

43

Stereochemical Recognition of Doubly Functional Aminotransferase in 2-Deoxystreptamine Biosynthesis

Yokoyama, Kenichi, Kudo, Fumitaka, Kuwahara, Mieko, Inomata, Kousuke, Tamegai, Hideyuki, Eguchi, Tadashi, Kakinuma, Katsumi

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 197 KB

english, 2005

44

Characterization of Polyphosphate Glucokinase SCO5059 from Streptomyces coelicolor A3(2)

KOIDE, Mai, MIYANAGA, Akimasa, KUDO, Fumitaka, EGUCHI, Tadashi

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2013

Language:

english

File:

PDF, 117 KB

english, 2013

45

Characterization and Mechanistic Study of a Radical SAM Dehydrogenase in the Biosynthesis of Butirosin

Yokoyama, Kenichi, Numakura, Mario, Kudo, Fumitaka, Ohmori, Daijiro, Eguchi, Tadashi

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 282 KB

english, 2007

46

Characterization of a Radical S -Adenosyl- l -methionine Epimerase, NeoN, in the Last Step of Neomycin B Biosynthesis

Kudo, Fumitaka, Hoshi, Shota, Kawashima, Taiki, Kamachi, Toshiaki, Eguchi, Tadashi

Journal:

Journal of the American Chemical Society

Year:

2014

Language:

english

File:

PDF, 401 KB

english, 2014

47

Analysis of the Molecular Recognition Features of Individual Modules Derived from the Erythromycin Polyketide Synthase

Wu, Nicholas, Kudo, Fumitaka, Cane, David E., Khosla, Chaitan

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 198 KB

english, 2000

48

Significance of the 20-kDa Subunit of Heterodimeric 2-Deoxy- scyllo -inosose Synthase for the Biosynthesis of Butirosin Antibiotics in Bacillus circulans

TAMEGAI, Hideyuki, NANGO, Eriko, KOIKE-TAKESHITA, Ayumi, KUDO, Fumitaka, KAKINUMA, Katsumi

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2002

Language:

english

File:

PDF, 612 KB

english, 2002

49

Engineering the synthetic potential of β-lactam synthetase and the importance of catalytic loop dynamics

Labonte, Jason W., Kudo, Fumitaka, Freeman, Michael F., Raber, Mary L., Townsend, Craig A.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

50

New glycosylated derivatives of versipelostatin, the GRP78/Bip molecular chaperone down-regulator, from Streptomyces versipellis 4083-SVS6

Zhao, Ping, Ueda, Jun-ya, Kozone, Ikuko, Chijiwa, Shuhei, Takagi, Motoki, Kudo, Fumitaka, Nishiyama, Makoto, Shin-ya, Kazuo, Kuzuyama, Tomohisa

Journal:

Organic & Biomolecular Chemistry

Year:

2009

Language:

english

File:

PDF, 172 KB

english, 2009

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